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Arthritis and Inflammation
Why Enzogenol and Arthritis
Enzogenols' powerful flavonoids possess
multiple anti-inflammatory activities making it an excellent choice as
a natural product in the treatment and control of inflammatory
disorders and sports related injuries.
These conditions include;
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 rheumatoid arthritis
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osteo arthritis
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juvenile
chronic arthritis
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asthma and severe kidney disease,
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amyloidosis and
inflammatory bowl disease
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lupus and fibromyalgia
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multiple sclerosis
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and others e.g. sports injuries
Enzogenol is full of specific flavonoids,
clinically shown to inhibit the deterioration of collagen II in those
who suffer from arthritis. This helps restore the balance of
deterioration and regeneration in the joints which adds up to
less pain for those who suffer and more functionality of the
joints.
Oxidative Stress has been shown to be a major factor in joint
inflammation. This stress usually begins to set in during our 20’s
and really starts to manifest as chronic problems by the time we
reach middle age, including rheumatoid and osteoarthritis. It’s
really like a ticking time bomb in your joints.
Enzogenol is packed with a whole range of antioxidants,
supplementing what your body is already producing and what you’re not
likely getting in your diet. In fact, to get the same amount of
antioxidants from your diet, you’d have to eat more than 4 kilos or 8
pounds of fruit and vegetables every day.
These antioxidants not only prevent daily deterioration from
oxidative stress, they also allow your body to renew and strengthen
your bones and joints.
Inflammation
Many pains besides Arthritis can be
caused by inflammation. Inflammation is characterized by swelling,
pain, localized heat, and redness. Injury could be a major catalyst
for inflammation. When injury occurs, fluid gets trapped in the
spaces between cells in the injured tissue. This fluid most often is
the result of leakage from capillaries, but it can also be produced
directly in tissue via free radical reactions.
Reduction in Swelling
Enzogenol helps normalize capillary permeability to prevent the
leakage of fluid that causes swelling. It also helps by neutralizing
free radicals that promote swelling and inflammation.
Enzogenol in the
therapy of inflammatory disorders?
Evidence for the role of Enzogenol in disorders of chronic inflammation
comes from many studies on the consequences of the elevated oxidant
levels. Biomarkers of cellular damage indicative of oxidative stress. Enzogenols
flavonoids are uniquely suited as a support or single therapy in the
treatment of inflammatory disorders due to their combination of super
powerful antioxidant and anti-inflammatory properties.
In conclusion
The reasons
to use Enzogenol in the management of arthtitis, fibromyalgia, lupus and
other inflammatory disorders include:
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In addition
to anti-inflammatory properties flavonoids may also have beneficial
effects in arthritic diseases by positively influencing the balance
between synthesis and degradation of extra-cellular cartilage
constituents. Evidence for this action comes from inhibition of type II
collagen breakdown.
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The radical
scavenging capacity of flavonoids, and particularly proanthocyanidins is
many times higher than that of the vitamin antioxidants for a wide
range of radicals.
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The potency as antioxidants and
the chemical diversity of multi-compound flavonoid extracts, like ENZO
Professional, strongly recommend flavonoids in therapeutic efforts to
lower oxidative stress levels.
-
Flavonoids
have been shown to inhibit the production of ROS, the activity of the ROS
generating enzymes MPO and NADPH oxidase, and several signal transducing
enzymes involved in the cell activation in neutrophils.
-
Flavonoids
have been shown to reduce biomarkers of oxidative cell damage in cell
culture systems, animal models and human studies.
-
Flavonoids
inhibit lipid peroxidation this can be by direct radical scavenging or by
chelation properties of transition metals.
-
Flavonoids
have direct anti-inflammatory properties that have been documented in many
studies. The anti-inflammatory properties of flavonoids include
cyclooxygenase.
Enzogenol flavonoids are very promising agents for
the management of arthritis and other inflammatory diseases. In addition, Enzogenol flavonoids
possess multiple anti-inflammatory activities making it an excellent
choice as a support agent in the treatment of inflammatory disorders.
MED Note
In the acute inflammatory response the production of this
entire battery of free radicals is an important mechanism
that is necessary to fight of invading pathogens. However,
the problems begin when the inflammatory process
persists and becomes chronic, because the inherently high
level of oxidative stress turns against the healthy body
tissues. In diseases, such as the different forms of arthritis
or in autoimmune disorders like lupus or multiple
sclerosis, where inflammation manifests chronically, free
radicals are permanently produced and have the capacity to
cause tissue destruction. It is in particular in these types of
diseases that managing oxidative stress levels should be
considered as part of the general therapy.
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