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Fantastic News
For Kids and Parents
Parents and Health
Practitioners have discovered Enzogenol as an effective
nutritional therapy to support children with symptoms
of hyperactivity, attention deficits and behaviour problems.
Several paediatricians specialising in the treatment of
children with ABC disorders have found Enzo Professional,
the high strength Enzogenol formulation, to be a very
useful adjunct treatment for children.
The ABC = Attention Behaviour Continuum comprises a number
of conditions that include Attention Deficit Disorder,
with and without Hyperactivity, Asperger's Syndrome, Autism
and other conditions that share similar behavioural phenotypes.
The Enzogenol trial results have given some initial evidence
that Enzogenol may improve brain activities naturally
to reach similar effects to Ritalin but without the drug-sledgehammer
and the risk of side effects.
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Dr. Leila Masson
from the Mother-Well Clinic in Auckland, New Zealand
had this to say about her experience:
“Enzogenol is a safe
and effective alternative to medication for children
with hyperactivity and problems concentrating. I
have noticed improvements in my patients within
a few weeks of starting this potent antioxidant.
Parents and teachers consistently report that the
children are calmer and more focused. I recommend
a trial of Enzogenol for any child with features
of ADHD or autism.”
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Autism spectrum disorders (ASDs) are neurodevelopmental
disorders characterised by difficulties in communication
and by repetitive and stereotypic behaviours, as well
as by social impairment, attention, cognitive, and learning
defects.
ASDs have increased significantly to 1/150 children, and
the reasons for this increase are still not clear. There
is no reliable screening test, and no definite pathogenesis
or curative therapy. However, a recent review of publications
on ASDs pathogenesis and treatment with emphasis on neuroimmune
processes and new therapeutic approaches found increased
oxidative stress and immune dysregulation are present
in ASDs, and unique combinations with antioxidant and
anti-inflammatory flavonoids hold promise for mitigating
ASD.
(Source: Theoharides TC, Kempuraj D, Redwood L; Autism:
an emerging 'neuroimmune disorder' in search of therapy.
Expert Opinion in Pharmacotherapy 2009;10(13):2127-43.)
Parents Feedback
Parents Feedback
The parents feedback has been great! More and
more children are reaping the benefits of being calmer,
more attentive and socialising much better with other
kids. The case studies attest to the success of Enzogenol
as part of a nutritional treatment approach. In all cases,
Enzo Professional was the preffered choice.
The case studies below
have been provided by the parents of the affected child
directly to Enzo Nutraceuticals Ltd using a case study
questionnaire. The parent gave consent for the information
to be used here as long as it is kept anonymous. The information
provided has not been altered in any other way.
Case Studies
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Case 11:
D. H., boy, age 6
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| Diagnosis:
Neurotypical,
struggling at school
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First
diagnosed at age:
6
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Medication
(pharmaceutical): None
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Supplementation
(nutritional):
Fish oil, Vitamin C, D3-drops, probiotic,
multivit, Biocidin, Pfeiffer Primer IV
(Zinc)
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ENZO Professional
Supplementation:
started
17 Nov 2008, 1 cap per day
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Special
way of dosing:
No
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OBSERVATIONS
1. Have
you seen any changes in your child after
starting on Enzo Professional?
YES!
If YES,
how long after starting Enzo Professional
did you notice changes? 3-4 weeks
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Please
describe changes: less "thick"
- retaining information better,
calmer, more capable. |
2. Have
you noticed any unwanted effects / side
effects from Enzo Professional?
No!
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3. Have
you noticed any changes on the following
after starting your child on Enzo Professional?
If so, please comment:
Hyperactivity:
No less
than normal.
Irritability:
Less.
Attention
span:
Better.
Concentration:
Better.
Listening
ability:
Selective hearing! a little.
Socialisation
skills:
Never a problem.
Discipline:
He's nicer.
School
performance:
Improved, not hugely but encouraging.
Sleep:
Always a good sleep.
Appetite:
Same.
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4. Is
there anything else you might have noticed
that you feel might be helpful to add
here?
School
report (Dec 08): has become more focussed,
showing more self discipline and independence
towards learning.
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Date this
questionnaire was filled out:
20 Dec 2008
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Case
10:
M. G., boy, age 16
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Diagnosis:
ADD
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First
diagnosed at age:
10
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Is your
child predominantly inattentive, predominantly
hyperactive-impulsive, or a combination
of both?
Inattentive.
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Medication
(pharmaceutical): None.
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Supplementation
(nutritional):
Omega 3
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ENZO
Professional Supplementation:
started
14 Oct 2008, 2 caps per day
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Special
way of dosing:
No.
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OBSERVATIONS
1. Have
you seen any changes in your child after
starting on Enzo Professional?
YES?
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Please
describe changes:
He said that he finds it easier to concentrate
after being on the tablets for 2 weeks.
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2. Have
you noticed any unwanted effects / side
effects from Enzo Professional?
No!
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3. Have
you noticed any changes on the following
after starting your child on Enzo Professional?
If so, please comment:
Attention
span:
Yes!
Concentration:
Yes!
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4. Is
there anything else you might have noticed
that you feel might be helpful to add
here? No.
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Date
this questionnaire was filled out:
28 Nov 2008
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Case
9:
N. P., boy, age 5
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Diagnosis:
ADHD
with oppositional defiance disorder
(Hyperactivity Major)
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First
diagnosed at age:
4
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Is your
child predominantly inattentive, predominantly
hyperactive-impulsive, or a combination
of both?
Hyperactive
/ impulsive / oppositional defiant.
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Medication
(pharmaceutical): Rubifen 10.
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Supplementation
(nutritional):
Probiotic,
Multivitamin, Vit C, Magnesium, Evwening
Primrose oil, Epsom Salt Baths, Zinc
Pfeiffer Primer IV, Flaxoil.
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ENZO
Professional Supplementation:
started
24 Sep 2008, 2 caps per day
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Special
way of dosing:
1 cap
morning straight after food,. Second
after lunch or 3 pm.
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OBSERVATIONS
1. Have
you seen any changes in your child after
starting on Enzo Professional?
YES.
If YES,
how long after starting Enzo Professional
did you notice changes? 1 day.
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Please
describe changes:
It appeared to work quickly - I noticed
once dosed in the morning he seemed
calmer in afternoon. At first I thought
that it was a fluke, but the next day
he seemed to be calmer, too. With the
calmness came better clearer speech.
Good listening, more receptive to requests
to comply. |
2. Have
you noticed any unwanted effects / side
effects from Enzo Professional?
No.
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3. Have
you noticed any changes on the following
after starting your child on Enzo Professional?
If so, please comment:
Hyperactivity:
Calmer.
Irritability:
Less.
Attention
span:
Much
better.
Concentration:
Much better.
Listening
ability:
Greatly improved.
Discipline:
Better - more receptive, compliant.
School
performance:
Better.
Sleep:
OK.
Appetite:
No noticable change.
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4. Is
there anything else you might have noticed
that you feel might be helpful to add
here?
I did
drop the afternoon rubifen 10 to see
what reaction we would get. He coped
so well that I continued it - only dosing
when the situation called for it.
Really happy with the result N has had,
will continue with this product as part
of his supplement regime. Most days
he has only 2/3 doses of Rubifen. N
starting school on 20th Nov. Many Thanks,
F.P.
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Date
this questionnaire was filled out:
10 Nov 2008
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Case
8:
T. B., boy, age 8
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Diagnosis:
mild
ADHD
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First
diagnosed at age:
2
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Is your
child predominantly inattentive, predominantly
hyperactive-impulsive, or a combination
of both?
Predominantly
inattentive.
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Medication
(pharmaceutical): None.
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Supplementation
(nutritional):
Magnesium,
Zinc, Vitamin C, Acidophilus, Fish oil
(daily), Multivitamin (2-3xwk)
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Other
modes of treatment:
Osteopathy,
meditation, homeopathy, naturopathy
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ENZO
Professional Supplementation:
started
12 Sep 2008, 1 cap per day (240mg)
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Special
way of dosing:
Swallows
capsule whole.
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OBSERVATIONS
1. Have
you seen any changes in your child after
starting on Enzo Professional?
YES.
If YES,
how long after starting Enzo Professional
did you notice changes? Difficult
to say.
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Please
describe changes:
More attentive, attempting to solve
problems instead of ignoring (e.g. can't
find shoes so finds a different pair),
calmer. |
2. Have
you noticed any unwanted effects / side
effects from Enzo Professional?
Could
his bowel be irritated? - Has had 1
episode of tummy bug and 1 episode of
irritable bowel this past 4 weeks.
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3. Have
you noticed any changes on the following
after starting your child on Enzo Professional?
If so, please comment:
Hyperactivity:
Calmer.
Attention
span:
More
attentive.
Concentration:
Reading for longer.
Listening
ability:
Improved.
Discipline:
Not sure!
School
performance:
Not sure!
Sleep:
Variable. |
Date
this questionnaire was filled out:
12 Oct 2008
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Case
7:
W. C., boy, age 9
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Diagnosis:
mild
Asperger's/hyperactive/obsessive compulsive.
Mainstream and doing well.
Just on the edge of the spectrum.
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First
diagnosed at age:
2
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Is your
child predominantly inattentive, predominantly
hyperactive-impulsive, or a combination
of both?
Hyperactive,
impulsive. Once he is on a track it
is hard to divert him. |
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Medication
(pharmaceutical): None.
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Supplementation
(nutritional):
PM Forte, Fish oil, Probiotics, Olive
leaf extract, biocidin
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Other
modes of treatment:
Homeopathy |
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ENZO
Professional Supplementation:
started
Oct 2007, 1 cap per day
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Special
way of dosing:
Swallows
pills.
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OBSERVATIONS
1. Have
you seen any changes in your child after
starting on Enzo Professional?
YES.
If YES,
how long after starting Enzo Professional
did you notice changes? Quite
quickly.
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Please
describe changes:
When you are doing so much it is tricky
to tell what is working, but my gut
tells me that the Enzo has been instrumental
in the latest strides forward that we
have made. I want to keep him on it. |
2. Have
you noticed any unwanted effects / side
effects from Enzo Professional?
No.
|
3. Have
you noticed any changes on the following
after starting your child on Enzo Professional?
If so, please comment:
Hyperactivity:
Much
better.
Listening
ability: Still problem.
Socialisation
skills:
Much better. |
Date
this questionnaire was filled out:
5 May 2008
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Case
6:
D. M-W., boy, age 8
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Diagnosis:
Asperger's
Syndrome / ADHD
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First
diagnosed at age:
6
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Is your
child predominantly inattentive, predominantly
hyperactive-impulsive, or a combination
of both?
Combination.
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Medication
(pharmaceutical): None.
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Supplementation
(nutritional):
Herbal anti-streptococcal mix, Biocidin,
Probiotic, B-complex, Magnesium, Fish
oil, Evening primrose oil, Zinc-Pfeiffer
primer, Selenium, DMG
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ENZO
Professional Supplementation:
started
Feb 2008, 2 caps per day
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Special
way of dosing:
Capsule
fine.
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OBSERVATIONS
1. Have
you seen any changes in your child after
starting on Enzo Professional?
YES? (Difficult to isolate if specifically
due to Enzo as other suppl started at
the same time.)
If YES,
how long after starting Enzo Professional
did you notice changes? not sure.
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Please
describe changes:
This year D is calmer, able to concentrate
in classroom setting for short periods.
Will comply with instructions.
|
2. Have
you noticed any unwanted effects / side
effects from Enzo Professional?
No!
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3. Have
you noticed any changes on the following
after starting your child on Enzo Professional?
If so, please comment:
Hyperactivity:
Few
episodes - was little problem.
Irritability:
This was a problem - major meltdowns.
Much more settled. Very few meltdowns.
Attention
span:
Longer now so can work/concentrate in
bursts 15min.
Concentration:
Can now work in classroom. Previously
had to be separated with teacher aid.
Listening
ability:
All
related.
Socialisation
skills:
A lot more confident and social. Can
play without having to dominate. Happy.
Proactively joining school clubs and
sport.
Discipline:
Far fewer "time outs". Will follow direction
when being told off.
School
performance:
He is doing work for the first time
since starting school! Huge change.
Sleep:
Still restless.
Appetite:
Always
big appetite.
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4. Is
there anything else you might have noticed
that you feel might be helpful to add
here?
I've been taking it (Enzo Professional)
and, perhaps wishful thinking, feel
sharper thinking.
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Date
this questionnaire was filled out:
11 April 2008
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Case
5:
J. C-S., boy, age 16
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Diagnosis:
Asperger's
Syndrome / ADHD
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First
diagnosed at age:
4
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Is your
child predominantly inattentive, predominantly
hyperactive-impulsive, or a combination
of both?
Combination
of both.
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Medication
(pharmaceutical):
|
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Supplementation (nutritional):
Vitamin C, D, Forte Nutrients, CoQ10,
B2, L-carnitine, N-Acetylcysteine -
200mg (6 a day), CMD trace mineral tablets,
iron, diet enzymes, OMG ultramuscleze,
probiotic, Vit E (400IU) |
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ENZO
Professional Supplementation:
started
Nov 2007, 4 caps per day (2 AM, 2 PM)
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Special
way of dosing:
J takes
tablets no problem.
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OBSERVATIONS
1. Have
you seen any changes in your child after
starting on Enzo Professional?
YES!
If YES,
how long after starting Enzo Professional
did you notice changes?
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Please describe changes: Much
calmer, notices things around him. More
energy in a positive way. J had food
poisoning as a baby & we have only been
doing the Biomedical for 5 1/2 years
so started late. As there were no Doctors
doing Biomedical when J was 4 years
old which is a shame as lead is not
good for the brain - IQ etc. That was
J's main problem & viruses. We have
got the lead out - now we are healing
the body, brain - I hope.
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2. Have
you noticed any unwanted effects / side
effects from Enzo Professional?
No!
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3. Have
you noticed any changes on the following
after starting your child on Enzo Professional?
If so, please comment:
Hyperactivity:
Less.
Irritability:
Less.
Attention
span:
Better.
Concentration:
Better.
Listening
ability:
Better.
Socialisation
skills:
Better.
Discipline:
Better.
School
performance:
Pleased with his behaviour. Academics
is still a problem.
Sleep:
Always been great.
Appetite:
Better.
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4. Is
there anything else you might have noticed
that you feel might be helpful to add
here?
How
long does this product need to be in
the system before you should notice
differences? More differences than about.
- 5 months on these meds now. Or will
there be slight improvements all the
time?
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Date
this questionnaire was filled out:
12 April 2008
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Case
4:
S. D., boy, age 8
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Diagnosis:
Asperger's
Syndrome (ASD) and ADD
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First
diagnosed at age:
3
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Is your
child predominantly inattentive, predominantly
hyperactive-impulsive, or a combination
of both?
Inattentive!
|
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Medication
(pharmaceutical):
None.
|
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Supplementation
(nutritional):
Vitamin C, probiotics, cod liver oil,
digestive enzymes, " ultra-muscle-eze"
(magnesium), mulivitamin ("kindervital"),
flaxseed oil, "neuro-care for kids",
melatonin, calcium
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Other
modes of treatment:
Brain-Gym exercises, gluten-free, casein-free
diet, no artificial flavourings, colourings,
preservatives
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ENZO
Professional Supplementation:
started
Feb 2008, 2 caps per day
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Special
way of dosing:
No,
just swallow with water.
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OBSERVATIONS
1. Have
you seen any changes in your child after
starting on Enzo Professional?
YES!
If YES,
how long after starting Enzo Professional
did you notice changes?
Immediate!
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Please
describe changes:
From the first few days we found that
S focused better and longer than before.
He is also better at interacting with
other children. His restless behaviour
decreased significantly. We had been
doing supplements and GF/DF diet for
7 months but it wasn't until we used
Enzogenol/Enzo Professional that we
saw a dramatic change in his ability
to focus. S is now doing very well in
school and learning classical guitar!
And he is in Cub Scouts!!
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2. Have
you noticed any unwanted effects / side
effects from Enzo Professional?
No!
|
3. Have
you noticed any changes on the following
after starting your child on Enzo Professional?
If so, please comment:
Hyperactivity:
Decreased
by a significant amount.
Irritability:
Much
more capable of controlling emotions.
Attention
span:
Greatly increased!
Concentration:
Much more clear-minded and able to focus.
Listening
ability:
No change - selective hearing!
Socialisation
skills:
Much improved due to not annoying others.
The greatest problem with socialisation
for S was that he couldn't stop annoying
other children by touching them, bumping
into them, spinning around, talking
too loudly, just constantly in motion.
Now he can sit quietly in a group and
not drive the other children crazy.
While this is normal for others, this
is a first for S!
Discipline:
Doesn't have tantrums anymore when reprimanded.
School
performance:
Greatly improved.
Sleep:
No change.
Appetite:
No
change. (has never had much of an appetite)
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4. Is
there anything else you might have noticed
that you feel might be helpful to add
here?
I wish
that we had known about this when S
was a toddler!! We could have saved
him and us a whole lot of grief! This
has truly been the turning point for
us.
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Date
this questionnaire was filled out:
11 April 2008
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Case
3:
D.
M., boy, age 6
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Diagnosis:
Autism
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First
diagnosed at age:
1 1/2
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Is your
child predominantly inattentive, predominantly
hyperactive-impulsive, or a combination
of both?
Both! |
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Medication
(pharmaceutical): -
|
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Supplementation
(nutritional):
Biomedical P5P, Zn, Mg
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ENZO
Professional Supplementation:
started Dec 2007, 1 cap per day
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Special
way of dosing:
Capsule given in mashed fruit. He swallows
it whole.
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OBSERVATIONS
1. Have
you seen any changes in your child after
starting on Enzo Professional?
YES!
If YES,
how long after starting Enzo Professional
did you notice changes?
1 week!
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Please
describe changes:
D is less hyperactive, more attentive
and calm. Concentration is better. He
wants to interact with other people.
Responds to people talking to him. He
is much more aware what is going on
around him.
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2. Have
you noticed any unwanted effects / side
effects from Enzo Professional?
No!
|
3. Have
you noticed any changes on the following
after starting your child on Enzo Professional?
If so, please comment:
Hyperactivity:
Less hyperactive!
Irritability:
Less irritable!
Attention
span:
Much better!
Concentration:
More concentration!
Listening
ability:
Yes, very much so!
Socialisation
skills:
Interested in things going on around
him!
Discipline:
Much better because of his listening!
School
performance:
Much
calmer!
Sleep:
He has always been a good sleeper, no
change!
Appetite:
Just the same!
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4. Is
there anything else you might have noticed
that you feel might be helpful to add
here?
Prior
to Enzo Professional D would only be
able to tolerate a trip to the shopping
mall, kids party or supermarket for
a max of 1 hour. Now he is great for
2-3 hours!!! Fabulous improvement.
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Date
this questionnaire was filled out:
12 April 2008
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Case
2:
A. W., girl, age 6
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Diagnosis:
A.S.D.
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First
diagnosed at age:
2 |
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Medication
(pharmaceutical):
Nilstat, Melatonin |
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Supplementation
(nutritional):
Vitamin C, Mg, Zn, Se, probiotic, iodine,
floradix, B12, Evening Primrose oil,
Cod Liver Oil
|
|
ENZO
Professional Supplementation:
started Nov 2007, 2 caps (1 am, 1 pm)
|
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Special
way of dosing:
Capsule content sprinkled onto a spoon
of soy yoghurt
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OBSERVATIONS
1. Have
you seen any changes in your child after
starting on Enzo Professional?
YES!
If YES,
how long after starting Enzo Professional
did you notice changes?
3 months!
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Please
describe changes:
Calmer. Happier. Complient. Focused
at school. Learning better.
|
2. Have
you noticed any unwanted effects / side
effects from Enzo Professional?
No!
|
3. Have
you noticed any changes on the following
after starting your child on Enzo Professional?
If so, please comment:
Hyperactivity:
No.
Irritability:
Yes. Much calmer!
Attention
span:
Yes. Much better!
Concentration:
Yes.
Improved!
Listening
ability:
Yes. Understands well!
Socialisation
skills:
Yes. Making friends!
Discipline:
Yes. Much more obedient!
School
performance:
Yes. Brilliant!
Sleep:
Yes. Sleeping through!
Appetite:
Yes. Eating breakfast.
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4. Is
there anything else you might have noticed
that you feel might be helpful to add
here?
Nice
company to deal with. Friendly + helpful.
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Date
this questionnaire was filled out:
11 April 2008
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Case
1:
J. C., boy, age 9 |
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Diagnosis:
A.D.H.D., Mild dyspaxia & dyslexic
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First
diagnosed at age:
7
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Is your
child predominantly inattentive, predominantly
hyperactive-impulsive, or a combination
of both?
Predominantly
hyperactive!
|
|
Medication
(pharmaceutical):
Previous Doctor suggested Ritalin -
I refused!
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Supplementation
(nutritional):
Iodine, Zn, Vitamin D, omega 3's
|
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ENZO
Professional Supplementation:
started Aug 2007, 1 cap per day
|
|
Special
way of dosing:
Straight as capsule with juice.
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OBSERVATIONS
1. Have
you seen any changes in your child after
starting on Enzo Professional?
YES!
If YES,
how long after starting Enzo Professional
did you notice changes?
1 week!
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Please
describe changes:
A whole lot calmer. Reading has improved.
Comprehension has improved. Listening
to instructions are better. Behaviour
improved by 100%. Even when he is on
Enzo Professional his behaviour will
deteriorate if he has chocolate or lollies
with colouring. We avoid additives etc...
But with Enzo huge improvement.
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2. Have
you noticed any unwanted effects / side
effects from Enzo Professional?
None, whatsoever!
|
3. Have
you noticed any changes on the following
after starting your child on Enzo Professional?
If so, please comment:
Hyperactivity:
Very calm now!
Irritability:
Less irritable!
Attention
span:
Improved!
Concentration:
Improved!
Listening
ability:
Improved!
Socialisation
skills:
Mixes with kids better!
Discipline:
A lot better. We rarely have to tell
him off compared to before!
School
performance:
Vast improvement!
Sleep:
Small improvement!
Appetite:
Eats like a horse!
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4. Is there anything else you might
have noticed that you feel might be
helpful to add here?
Before starting on Enzo his reading
was extremely difficult. Since then
his reading has improved amazingly.
We finally have hope & his confidence
in Maths and reading have improved too.
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Date
this questionnaire was filled out:
13 April 2008
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Safety
Enzogenol® has no harmful side effects, unlike caffeine,
amphetamines and other cognitive enhancers such as Ritalin.
Enzogenol® does not increase blood pressure or heart rate,
stunt growth in children, nor does it have any potential
to be addictive.
The Science
The latest clinical
study on Enzogenol has investigated effects on cognitive
function in healthy people (Pipingas et al. 2008). This
study demonstrated improved performance on cognitive tasks
after only 5 weeks of treatment.
Important for the application in ADHD, Asperger’s and
Autism are the results from the neuroimaging analyses.
The Enzogenol study used steady-state probe topography
(SSPT) neuroimaging to investigate changes in brain activity
associated with the treatment.
This is a powerful technique established at the Brain
Sciences Institute (BSI) of Swinburne University in Melbourne.
With this method the researchers found significant changes
in patterns of brain activity that were associated with
the improved performance. Professor Silberstein of BSI
had previously studied the effects of methylphenidate
(Ritalin) on brain activities in children with ADHD using
the same technology, and found specific changes in the
way the kid’s brains worked after an acute dose of Ritalin.
It is these
effects of the drug in the brain that lead to the normalization
in behaviour and allow the children to concentrate better.
Interestingly, very similar changes were seen with the
Enzogenol, but these changes observed with Enzogenol were
milder and more supple than those observed with the drug
Ritalin.
These results have given some initial evidence that Enzogenol
may improve brain activities naturally to reach similar
effects to Ritalin but without the drug-sledgehammer and
the risk of side effects.
At this time we can only speculate on the possible
mechanisms of action that could explain the positive effects
Enzogenol has on children with behavioural problems. Possibilities
include:
-
Affecting the antioxidant status – reducing free radical
oxidative stress.
-
Direct effects modifying signal transduction in the
CNS from phenolic compounds and their metabolites entering
circulation.
-
Indirect effects by influencing the gut-brain axis,
i.e.
-
reducing leaky gut symptoms that may contribute to,
or underlie, the behavioral phenotype.
-
affecting levels of circulating neuroactive compounds
originating from the enteric nervous system.
-
modifying/reducing negative effects of dietary antigens.
-
affecting metal load in the gut through strong metal-chelating
properties of the proanthocyanidin compounds in Enzogenol.
But...Enzogenol does
appear to work!
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